New genetic study confirms that alcohol is a direct cause of cancer Nuffield Department of Population Health

New genetic study confirms that alcohol is a direct cause of cancer Nuffield Department of Population Health

study alcohol cancer

It can impair nutrient and vitamin absorption, alter hormone levels, and even make it easier for harmful chemicals to penetrate cells in the mouth and throat. It can affect the bacteria in our guts, the so-called microbiome, that we live with and is important for our health and well-being. Of particular concern is the rising incidence of early-onset colorectal cancer among adults under 50. What that means is that nations in those areas of Africa should be thinking now about strategies to control drinking. “Currently, only 16 of 46 countries in sub-Saharan Africa have national alcohol strategies,” says Rumgay. However, a standard drink looks different depending on what type of alcohol you are drinking.

Born to drink? What your finger length reveals about your relationship with alcohol

In addition, a proportion of KER’s time was funded by Bloomberg Philanthropies as part of the Bloomberg Initiative to Reduce Tobacco Use (). Neither funder had any role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript or adjunct articles. However, the predominant theme in the literature was that of perseverance and defiance. Around half of the sources included in our study actually talked about how the targets of intimidation responded. And most of those reported fighting back by exposing the tactics, correcting misinformation and launching their own legal challenges against the perpetrators.

things to know about alcohol and cancer

Drinking 20 to 60 grams, two to six drinks, of ethanol alcohol per day, which the authors defined as “risky drinking,” represented 39.4% of alcohol-attributable cancer cases. Moderate drinking – defined as 20 or fewer grams, or up to two drinks, per day – contributed to nearly 14%, or 1 in 7, cases. And the highest rates of alcohol-attributable cancers were among men who drank 30 to 50 grams of ethanol alcohol per day, and in women who consumed 10 to 30 grams every day.

While Bevers says studies show that alcohol is a risk factor for certain cancers, the link between alcohol and cancer recurrence is not known, especially for those who have completed cancer treatment. While she says the best way to reduce cancer risk is not drinking alcohol, drinking less can have a positive impact. For example, in the case of liver cancer, heavy alcohol consumption is known to cause cirrhosis, a chronic condition in which healthy cells in the liver are replaced with scar tissue, often causing inflammation and ultimately, leading to liver cancer. A study published in December 2020 in the International Journal of Environmental Research and Public Health showed that 60 percent of respondents reported increased drinking during the pandemic. (Thirteen percent said they were drinking less.) The study also showed that 34 percent of respondents reported binge drinking and 7 percent reported extreme binge drinking. Numerous studies indicated that people were drinking more alcohol, with stress, increased access, and boredom cited as factors.

  1. To evaluate the overall effects of alcohol on the cancer risk of a population, one must accurately quantify its effects on various types of tumors.
  2. Statistically significant means that the observed result would occur by chance under hypothesized conditions less than a specified proportion of the time (usually 5 percent).
  3. The authors received no specific funding for this work and declared no conflicts of interest.
  4. Alcohol is causally linked to many cancer types, but trends in alcohol consumption patterns change over time and between geographic regions.
  5. Department of Agriculture have defined moderate drinking as no more than one drink per day for women and no more than two drinks per day for men.

In terms of risk assessment, this meta-analysis confirms that high levels of alcohol consumption (i.e., more than four drinks per day) result in a substantial risk of cancer development at several sites. At the same time, other studies have shown that moderate alcohol consumption can have protective effects against certain types of heart disease. Accordingly, one must determine whether moderate alcohol consumption results in an overall favorable or unfavorable risk-benefit balance for the individual drinker or an entire population. This balance depends on the age, gender, and baseline disease rates among the members of a given population. Consequently, any definite risk-benefit assessment for moderate alcohol drinking requires much more far-reaching analyses that are beyond the scope of this article but that in the future may provide important information from a public health perspective.

Between 28% and 45% of East Asian people, for example, carry a variant of the ALDH2 enzyme that has been linked with a higher risk of developing cancers in the upper aerodigestive tract, the authors wrote. However, based on more recent, comprehensive studies, public health experts now generally agree that alcohol—including wine—does not have a so-called “cardioprotective” effect. Nevertheless, the research team also asked participants about the purported heart health benefits of alcohol, to see if it was related to their awareness about alcohol and cancer risk. To evaluate the overall effects of alcohol on the cancer risk of a population, one must accurately quantify its effects on various types of tumors. To this end, researchers have performed comprehensive meta-analyses of published studies investigating the relationship between alcohol intake and the risk for numerous types of cancer. Meta-analyses are studies that pool data from several studies, thereby substantially enhancing the overall number of cases evaluated.

study alcohol cancer

Shots – Health News

It is possible, however, that for breast cancer and other types of cancer related to disturbances in female hormone levels, alcohol may act by altering the metabolism and blood levels of female hormones, such as estrogen (Longnecker 1994). Moreover, a recent study suggests that the association may be limited to women with a family history of breast cancer (Vachon et al. 2001). Alcohol consumption also has been linked to cancers of the large bowel (i.e., colon and rectum) in both men and women and to breast cancer in women, although these associations have not yet been proven unequivocally.

And not only do women usually experience the immediate effects of alcohol more quickly than men, but they are also at a higher risk for alcohol’s long-term health effects. Researchers and health professionals can do more to help break down these misconceptions, Dr. LoConte added. “We need to really make sure that we reinforce the message that all alcohol increases cancer risk,” she said. As discussed during the workshop and webinar, studies have shown that only 33 to 46 percent of Americans are aware of the connections between alcohol and cancer risk. It was also easy to ignore a steady drumbeat of studies that showed that alcohol consumption is undeniably linked to cancer risk.

The first mutation is a loss-of-function mutation in the gene for the enzyme aldehyde dehydrogenase 2 (ALDH2). In the United States, a standard drink frequently is defined as 0.5 ounces (oz) or 14 grams of pure alcohol. This alcohol amount is found in 12 fluid oz of beer, 5 fluid oz of wine, and 1.5 fluid oz of 80-proof distilled spirits. A person’s risk of alcohol-related cancers is influenced by their genes, specifically the genes that encode enzymes involved in metabolizing (breaking down) alcohol (27).

The majority were not papers specifically about intimidation, but most were about corporate interference in policy passage or implementation. The remaining third were sources like blogs, newspaper articles, news stories in peer-reviewed journals, a case study, a press release, a recorded seminar and a book. Our new paper, published in Health Promotion International, reveals how researchers producing evidence of the harms of these industries have been intimidated because of their work. The survey findings come from APPC’s nationally representative Annenberg Science and Public Health (ASAPH) Knowledge How Long Does Molly MDMA Stay In Your System survey, which was conducted with a panel of more than 1,700 U.S. adults in September 2024.

But despite the significant personal and professional costs of working in an environment where their credibility is constantly questioned, researchers and advocates persevere. Rather, it’s about being aware of the potential risks and making choices that align with our health goals. In 2019, more than one in 20 cancer diagnoses in the West were attributed to alcohol consumption, and this is increasing with time. This figure challenges the widespread perception of alcohol as a harmless social lubricant and builds on several well-conducted studies linking alcohol consumption to cancer risk. While such public policies are effective and necessary, says Dr. Amy Justice, professor of medicine and public health at Yale University, we need to go further. Justice wrote a commentary in Lancet Oncology accompanying the alcohol-related cancer study.