Facility Cleaning News

Dr. Gonzalez explains the causes of elevated blood pressure in kids are likely a combination of modifiable factors, like diet, exercise, and obesity. In some kids, non-modifiable factors play a role, including health issues that might impact blood pressure, such as endocrine disease, renal disease, cardiac disease, and genetics. According to Vincent J. Gonzalez, MD, a pediatric and adult congenital cardiologist at Children’s Nebraska, the factors what does alcohol do to your blood pressure driving this trend are likely multifactorial. He points out that the research findings highlighted certain elevated risk factors, such as the fact that children with severe obesity were most likely to experience high blood pressure and males were more likely to be diagnosed than females. Regularly consuming too many calories can lead to weight gain and therefore obesity, which is a risk factor for heart attack, stroke and type 2 diabetes.

Buckman 2015 published data only

• We classified seven studies as having unclear risk of performance bias (Bau 2005; Bau 2011; Cheyne 2004; Dumont 2010; Karatzi 2005; Mahmud 2002; Maule 1993).
• However, even people who do not drink regularly have a risk of experiencing negative effects from alcohol.
• The aim of Bau 2011 was to determine the effects of alcohol on heart rate variability, so study authors did not measure and report DBP.

The sample size in the meta‐analysis for low‐dose comparison was not adequate to assess the effects of low doses of alcohol on BP and HR; however, we believe that the direction of the change in BP and HR was correct. For medium doses and high doses of alcohol, participants represented a range in terms of age, sex, and health condition. Because the participant population comprised predominantly young and healthy normotensive men, the overall evidence generated in this review cannot be extrapolated to women and older populations with other comorbidities.

Agewall 2000 published data only

First, there was the possibility of undesired bias and imprecision due to imputations of missing statistics. Most of the included studies did not report the standard error (SE)/standard deviation (SD) of the mean difference (MD) for the outcomes of interest. As described in our protocol, when we were unable to obtain the required SE/SD from study authors or by calculation from the reported P value or 95% CI, we imputed data according to the pre‐specified imputation hierarchy. We most often used the reported endpoint SE/SD value to impute the SE/SD of MD.

How alcohol affects blood pressure and the heart

Many short-term trials that randomly assign people to drink either alcohol or a nonalcoholic beverage show lower blood sugar levels and better insulin sensitivity among people who drink moderate amounts of alcohol. While these biomarkers aren’t a perfect representation of diabetes risk, they’re pretty close, says Dr. Mukamal. People with diabetes are twice as likely to have heart disease as people without the condition. Interestingly, https://ecosoberhouse.com/ the strength of this association was not consistent across different geographic regions. Alcohol use was protective against CHD for subjects in most countries, except for people of South Asian ethnicity living in South Asia (India, Bangladesh, Nepal, Pakistan, and Sri Lanka). INTERHEART results also suggested that the protective effect of any alcohol use against MI was greater in women and those over age 45.

• Even though Dumont 2010 mentioned blinding of outcome assessors, it is not clear whether blinding of outcome assessment was maintained in the case of blood pressure and heart rate measurements.
• Drinking more than one or two drinks in a sitting has been directly linked to a rapid rise in blood pressure, which in someone with very high levels of hypertension can lead to stroke.
• If your heart muscle is droopy and stretched, it cannot pump blood around your body very well.
• In addition, data from studies using new research methods, including Mendelian randomization, suggest that the relationship between low-to-moderate alcohol consumption and cardioprotection merits more critical appraisal (Holmes et al. 2014).
• However, he notes, that most cases of high blood pressure in kids are caused by primary or idiopathic hypertension.

Other risks of alcohol use

It also regulates metabolism, immune function, and inflammatory pathways. Hypertension, or high blood pressure, is a very common condition worldwide. “The best ways to maintain good health and lower blood pressure is by maintaining a healthy weight, exercising regularly, and maintaining a good diet that is low in salt and predominantly made up of unprocessed foods,” Amin said. “If you have high blood pressure, it’s probably in your best interest to drink minimally,” Morledge said. Alcohol also stimulates the release of adrenaline and puts the body in a fight-or-flight mode, leading to elevated blood pressure. According to a 2018 study and the World Health Organization, no amount of alcohol intake is safe, so any amount may be considered too much.

As a result, we were not able to quantify the magnitude of the effects of alcohol on men and women separately. This is unfortunate, as we have reason to believe that the effects of alcohol on BP might be greater in women. Several clinical trials in humans and studies conducted in animal models have reported stimulation of the sympathetic nervous system and increased noradrenaline after consumption of alcohol (Barden 2013; Grassi 1989; Randin 1995; Russ 1991; Zhang 1989). When noradrenaline stimulates the adrenergic receptors located in the heart muscles, heart rate and blood pressure are increased. We are also moderately certain that high‐dose alcohol decreased blood pressure within six hours, and the effect lasted up to 12 hours.

• Only three of these studies measured BP at various time points and found that alcohol has a hypotensive effect lasting up to five hours after alcohol consumption and a hypertensive effect 20 hours after alcohol consumption that lasts until the next day.
• For multi‐arm trials, if a study reported more than one intervention arm, we identified the relevant intervention arm and included that in the review.
• According to the World Health Organization (WHO), around 2.3 billion people globally drink alcohol, and most of them are from the European region.
• Including both of these doses or de‐selecting either one of these doses from Rosito 1999 from Analysis 2.1 and Analysis 2.2 (medium doses of alcohol) resulted in the same statistically significant conclusion.

Greyling 2016 published data only

Older adults — drinkers, nondrinkers, it doesn’t matter — are already at risk for hypertension. Research suggests that 74.5 percent of people 60 and older have high blood pressure, compared with 54.5 percent of adults ages 40 to 59. Several factors are to blame, one being your body’s network of blood vessels, which changes with age. The last thing you want is for that casual drink after work or glass of wine at dinner to negatively impact your heart health.

Bradford 1990 published data only

Increase heart rate

• Evidence of oxidative stress is found after short periods of alcohol consumption (2 to 18 weeks), at least in animal models.
• However, Dr. Cho points out that more recent data shows that there may be no amount of alcohol that is truly safe.
• Hering 2011, Carter 2011, and Spaak 2008 reported an increase in muscle sympathetic nervous activity (MSNA), which persists for at least 10 hours after consumption.
• The sample size in the meta‐analysis for low‐dose comparison was not adequate to assess the effects of low doses of alcohol on BP and HR; however, we believe that the direction of the change in BP and HR was correct.
• When blood pressure decreases, these receptors help minimize how much the blood vessels stretch to increase blood pressure.
• As noted in the text, the exact amount and duration of alcohol consumption that results in ACM in human beings varies.